Publications

RECENT PUBLICATIONS (2007)

1. Tran HA, Eikelboom JW. Role of protein z in stroke. Curr Treat Options Cardiovasc Med. 2007 Jun;9(3):191-7. PMID: 17601382 [PubMed - in process]

2. Catalano A, Dawson MA, Somana K, Opat S, Schwarer A, Campbell LJ, Iland H. The PRKAR1A gene is fused to RARA in a new variant acute promyelocytic leukemia. Blood. 2007 Aug 21; [Epub ahead of print] PMID: 17712046 [PubMed - as supplied by publisher]

3. van der Merwe J, Leong JY, Kaye D, Opat S, Bergin PJ, Taylor AJ, Rosenfeldt F. Antioxidant therapy for severe cardiac failure induced by iron overload secondary to dyserythropoietic anaemia. Heart Lung Circ. 2007 Oct;16(5):394-7. Epub 2007 Feb 20. PMID: 17314073 [PubMed - in process]

4. Morschhauser F, Seymour JF, Kluin-Nelemans HC, Grigg A, Wolf M, Pfreundschuh M, Tilly H, Raemaekers J, van 't Veer MB, Milpied N, Cartron G, Pezzutto A, Spencer A, Reyes F, Dreyling M. A phase II study of enzastaurin, a protein kinase C beta inhibitor, in patients with relapsed or refractory mantle cell lymphoma. Ann Oncol. 2007 Sep 28; [Epub ahead of print]

5. Orlowski RZ, Nagler A, Sonneveld P, Blade J, Hajek R, Spencer A, San Miguel J, Robak T, Dmoszynska A, Horvath N, Spicka I, Sutherland HJ, Suvorov AN, Zhuang SH, Parekh T, Xiu L, Yuan Z, Rackoff W, Harousseau JL. Randomized phase III study of pegylated liposomal doxorubicin plus bortezomib compared with bortezomib alone in relapsed or refractory multiple myeloma: combination therapy improves time to progression. J Clin Oncol. 2007 Sep 1;25(25):3892-901. Epub 2007 Aug 6.

6. Com E, Lagadec C, Page A, El Yazidi-Belkoura I, Slomianny C, Spencer A, Hammache D, Rudkin BB, Hondermarck H. Nerve growth factor receptor TrkA signaling in breast cancer cells involves KU70 to prevent apoptosis. Mol Cell Proteomics. 2007 Jul 7; [Epub ahead of print] PMID: 17617666 [PubMed - as supplied by publisher]

7. Spencer A, Reed K, Arthur C. Pilot study of an outpatient-based approach for advanced lymphoma using vinorelbine, gemcitabine and filgrastim. Intern Med J. 2007 Nov;37(11):760-6. Epub 2007 Jun 2. PMID: 17542998 [PubMed - in process]

8. Slavin MA, Grigg AP, Schwarer AP, Szer J, Spencer A, Sainani A, Thursky KA, Roberts AW. A randomized comparison of empiric or pre-emptive antibiotic therapy after hematopoietic stem cell transplantation. Bone Marrow Transplant. 2007 Jul;40(2):157-63. Epub 2007 Apr 30. PMID: 17468774 [PubMed - indexed for MEDLINE]

9. Baker ML, Allen P, Shortt J, Lewin SR, Spencer A. Immune recovery uveitis in an HIV-negative individual. Clin Experiment Ophthalmol. 2007 Mar;35(2):189-90. PMID: 17362465 [PubMed - indexed for MEDLINE]

10. Sharkey J, Khong T, Spencer A. PKC412 demonstrates JNK-dependent activity against human multiple myeloma cells. Blood. 2007 Feb 15;109(4):1712-9. Epub 2006 Oct 10. PMID: 17032922 [PubMed - indexed for MEDLINE]

11. Baulch-Brown C, Molloy TJ, Yeh SL, Ma D, Spencer A. Inhibitors of the mevalonate pathway as potential therapeutic agents in multiple myeloma. Leuk Res. 2007 Mar;31(3):341-52. Epub 2006 Sep 22. PMID: 16996129 [PubMed - in process]

12. Wei A, Cowie T. Rituximab responsive immune thrombocytopenic purpura in an adult with underlying autoimmune lymphoproliferative syndrome due to a splice-site mutation (IVS7+2 T>C) affecting the Fas gene. Eur J Haematol. 2007 Oct;79(4):363-6. Epub 2007 Aug 28. PMID: 17725802 [PubMed - in process]

13. Branford S, Hughes T, Milner A, Koelmeyer R, Schwarer A, Arthur C, Filshie R, Moreton S, Lynch K, Taylor K. Efficacy and safety of imatinib in patients with chronic myeloid leukemia and complete or near-complete cytogenetic response to interferon-alpha. Cancer. 2007 Aug 15;110(4):801-8. PMID: 17607681 [PubMed - indexed for MEDLINE]

14. Moore J, Nivison-Smith I, Goh K, Ma D, Bradstock K, Szer J, Durrant S, Schwarer A, Bardy P, Herrmann R, Dodds A. Equivalent survival for sibling and unrelated donor allogeneic stem cell transplantation for acute myelogenous leukemia. Biol Blood Marrow Transplant. 2007 May;13(5):601-7. Epub 2007 Mar 23. PMID: 17448920 [PubMed - indexed for MEDLINE]

15. Etto TL, Stewart LA, Nguyen TH, Williamson NA, Purcell AW, Schwarer AP. Expression and purification of the minor histocompatibility antigen, HA-1H generated in Escherichia coli. Protein Expr Purif. 2007 Jul;54(1):176-82. Epub 2007 Feb 27. PMID: 17428678 [PubMed - indexed for MEDLINE]

16. Dawson MA, Schwarer AP, McLean C, Oei P, Campbell LJ, Wright E, Shortt J, Street AM. AIDS-related plasmablastic lymphoma of the oral cavity associated with an IGH/MYC translocation--treatment with autologous stem-cell transplantation in a patient with severe haemophilia-A. Haematologica. 2007 Mar;92(3 Suppl):ECR06. PMID: 17405744 [PubMed - in process]

17. Barraclough KA, Dowling JP, Schwarer AP, Perry GJ. Sequential autologous peripheral blood stem cell transplantation and kidney transplantaion of light chain deposition disease. Nephrol Dial Transplant. 2007 Apr;22(4):1268-9. Epub 2006 Nov 16. No abstract available. PMID: 17110404 [PubMed - indexed for MEDLINE]

18. Thomas S, Herbert D, Street A, Barnes C, Boal J, Komesaroff P. Attitudes towards and beliefs about genetic testing in the haemophilia community: a qualitative study. Haemophilia. 2007 Sep;13(5):633-41. PMID: 17880455 [PubMed - in process]

19. Favaloro EJ, Bonar R, Duncan E, Earl G, Low J, Aboud M, Just S, Sioufi J, Street A, Marsden K. Mis-identification of factor inhibitors by diagnostic haemostasis laboratories: recognition of pitfalls and elucidation of strategies. A follow up to a large multicentre evaluation. Pathology. 2007 Oct;39(5):504-11. PMID: 17886101 [PubMed - in process]

20. Favaloro EJ, Bonar R, Meiring M, Street A, Marsden K; RCPA QAP in Haematology. 2B or not 2B? Disparate discrimination of functional VWF discordance using different assay panels or methodologies may lead to success or failure in the early identification of type 2B VWD. Thromb Haemost. 2007 Aug;98(2):346-58. PMID: 17721617 [PubMed - in process]

21. Mitra B, Mori A, Cameron PA, Fitzgerald M, Street A, Bailey M. Massive blood transfusion and trauma resuscitation. Injury. 2007 Sep;38(9):1023-9. Epub 2007 Jun 18. PMID: 17572415 [PubMed - in process]

22. Favaloro EJ, Lloyd J, Rowell J, Baker R, Rickard K, Kershaw G, Street A, Scarff K, Barrese G, Maher D, McLachlan AJ Comparison of the pharmacokinetics of two von Willebrand factor concentrates [Biostate and AHF (High Purity)] in people with von Willebrand disorder. A randomised cross-over, multi-centre study. Thromb Haemost. 2007 Jun;97(6):922-30. PMID: 17549293 [PubMed - indexed for MEDLINE]

23. Shortt J, Dunkley S, Rickard K, Baker R, Street A. Efficacy and safety of a high purity, double virus inactivated factor VIII/von Willebrand factor concentrate (Biostate) in patients with von Willebrand disorder requiring invasive or surgical procedures. Haemophilia. 2007 Mar;13(2):144-8. PMID: 17286766 [PubMed - indexed for MEDLINE]

24. Olavarria E, Siddique S, Griffiths MJ, Avery S, Byrne JL, Piper KP, Lennard AL, Pallan L, Arrazi JM, Perz JB, O'shea D, Goldman JM, Apperley JF, Craddock CF. Post-transplant imatinib as a strategy to postpone the requirement for immunotherapy in patients undergoing reduced intensity allografts for chronic myeloid leukemia. Blood. 2007 Sep 19; [Epub ahead of print] PMID: 17881635 [PubMed - as supplied by publisher]

25. Dawson MA, Avery S, McQuilten ZK, Bailey MJ, Shortt J, Polizzotto MN, Wood EM, Cole-Sinclair MF. Blood transfusion requirements for patients undergoing chemotherapy for acute myeloid leukemia how much is enough? Haematologica. 2007 Jul;92(7):996-7. PMID: 17606456 [PubMed - indexed for MEDLINE]

26. Paterson MA, Horvath AJ, Pike RN, Coughlin PB. Molecular characterization of centerin, a germinal centre cell serpin. Biochem J. 2007 Aug 1;405(3):489-94.

27. Daniel, P.B., Lux, W., Samson, AL., Schleuning, W.D., Niego, B., Weiss T.W, Tjärnlund-Wolf, A., and Medcalf, R.L. (2007). Two conserved regions within the tissue-type plasminogen activator gene promoter mediate regulation by brain-derived neurotrophic factor. /FEBS J /. IF = 3.164). 274:2411-2423.

28. Medcalf R.L. (2007). Fibrinolysis, inflammation and regulation of the plasminogen activating system. /J. Thromb. Haemostasis /Suppl 1:132-42.

29. Medcalf R.L.(2007). All thrombolytics are equal….or are we sure? Pharmacological essentials. Cerebrovascular Diseases 23 (suppl) 7-11.

30. Kendall JD, Rewcastle GW, Frederick R, Mawson C, Denny WA, Marshall ES, Baguley BC, Chaussade C, Jackson SP, Shepherd PR. Synthesis, biological evaluation and molecular modelling of sulfonohydrazides as selective PI3K p110alpha inhibitors. Bioorg Med Chem. 2007 Sep 4; [Epub ahead of print] PMID: 17869522 [PubMed - as supplied by publisher]

31. Jackson SP, Calkin AC. The clot thickens-oxidized lipids and thrombosis. Nat Med. 2007 Sep;13(9):1015-6.

32. Kim S, Garcia A, Jackson SP, Kunapuli SP.Insulin-like growth factor-1 regulates platelet activation through PI 3-K{alpha} isoform. Blood. 2007 Sep 7; [Epub ahead of print] PMID: 17827385 [PubMed - as supplied by publisher]

33. Schoenwaelder SM, Ono A, Sturgeon S, Chan SM, Mangin P, Maxwell MJ, Turnbull S, Mulchandani M, Anderson K, Kauffenstein G, Rewcastle GW, Kendall J, Gachet C, Salem HH, Jackson SP. Identification of a unique co-operative phosphoinositide 3-kinase signalling mechanism regulating integrin alpha IIb beta 3 adhesive function in platelets. J Biol Chem. 2007 Sep 28;282(39):28648-58.

34. Kulkarni S, Woollard KJ, Thomas S, Oxley D, Jackson SP. Conversion of platelets from a proaggregatory to a proinflammatory adhesive phenotype: role of PAF in spatially regulating neutrophil adhesion and spreading. Blood. 2007 Sep 15;110(6):1879-86.

35. Arcaro A, Doepfner KT, Boller D, Guerreiro AS, Shalaby T, Jackson SP, Schoenwaelder SM, Delattre O, Grotzer MA, Fischer B. Novel role for insulin as an autocrine growth factor for malignant brain tumour cells. Biochem J. 2007 Aug 15;406(1):57-66.

36. Chaussade C, Rewcastle GW, Kendall JD, Denny WA, Cho K, Gronning LM, Chong ML, Anagnostou SH, Jackson SP, Daniele N, Shepherd PR. Evidence for functional redundancy of class IA PI3K isoforms in insulin signalling. Biochem J. 2007 Jun 15;404(3):449-58.

37. Jackson SP. The growing complexity of platelet aggregation. Blood. 2007 Jun 15;109(12):5087-95. Review.

38. Bassler N, Loeffler C, Mangin P, Yuan Y, Schwarz M, Hagemeyer CE, Eisenhardt SU, Ahrens I, Bode C, Jackson SP, Peter K. A mechanistic model for paradoxical platelet activation by ligand-mimetic alphaIIb beta3 (GPIIb/IIIa) antagonists. Arterioscler Thromb Vasc Biol. 2007 Mar;27(3):e9-15.

39. Hughan SC, Hughes CE, McCarty OJ, Schweighoffer E, Soultanova I, Ware J, Tybulewicz VL, Watson SP. GPVI potentiation of platelet activation by thrombin and adhesion molecules independent of Src kinases and Syk. Arterioscler Thromb Vasc Biol. 2007 Feb;27(2):422-9.

40. Hughan SC, Watson SP. Differential regulation of adapter proteins Dok2 and Dok1 in platelets, leading to an association of Dok2 with integrin alphaIIbbeta3. J Thromb Haemost. 2007 Feb;5(2):387-94.

 41. Hamilton, J.R., Kaplan, Z., Jackson, S.P. and Opat, S. (2007) Antiplatelet Therapy: Current Status and Future Prospects. /Expert Opinion on Drug Discovery/. 2, 1035-1040.

42. Busso, N., Frasnelli, M., Feifel, R., Cenni, B., Steinhoff, M., Hamilton, J.R. and So, A. (2007) Evaluation of protease-activated receptor 2 (PAR2) in murine models of arthritis. /Arthritis Rheum/. 56, 101-107.

43. Book Chapter - Adhesion of Circulating Leukocytes and Platelets to the Vessel Wall Susan L. Cranmer and Gerard B.Nash Pages 153-170 (in Section "Cell Mechanics" ) Handbook of Hemorrheology and Hemodynamics . Publishers IOS Press, The Netherlands. Editors Baskurt, OK, Hardeman MR, Rampling MW and Meiselman HJ (2007)

44. Golledge J, Muller J, Shephard N, Clancy P, Smallwood L, Moran C, Dear AE, Palmer L, Normal P. “Association Between Osteopontin and Human Abdominal Aortic Aneurysm”. Art Throm Vasc Biol 27:655-60 (2007). (IF 7.400).

45. Lindemann, R.K., A. Newbold, A., Whitecross, K.F., Cluse, L.A., Frew, A.J., Ellis, L., Williams S., Wiegmans, A., Dear, A.E., Scott, C.L., Pellegrini, M.. Wei, A., Marks, P.A., Richon, V.M., Lowe, S.W., Smyth, M.J., and Johnstone, R.W. “Mechanistic analysis of the apoptotic and therapeutic activities of histone deacetylase inhibitors using a genetically tractable mouse model of B cell lymphoma”. Pro Nat Acad Sci USA 104:8071-6 (2007) (IF 10.231).

46. Vinh A, Gaspari T, Widdop R, Liu HB, Dousha L and Dear AE. “Novel Inhibitors of Histone Deacetylase Activity Reduce Abdominal Aortic Aneurism Formation and Progression in APOE Deficient Mice”. (In Press J Vasc Res August 2007). (IF 2.824).

47. Liu HB Yushan Y, Simpson RW, and Dear AE. “GLP-1 Attenuates TNF-mediated Induction of PAI-1 Expression ”. (In Press J Endo September 2007). (IF 3.072).

48. Dear AE and Byron K. Letter: “Genotype and Adverse Drug Reactions”. Med J Aust 187:61-2 (2007) (IF 2.000).